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The All-In-One Guide To PDE-5 Hormone Inhibitors

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Updated on
Written By ericawilson30ew
Table Of Content
  • What Exactly Are PDE-5 Hormone-Inhibitory Drugs?
  • Purpose Of Using PDE-5 Hormone Inhibitor Pills
  • How Do PDE-5 Hormone Inhibitors Work?
  • Popular Medicines And Categories Of Medicines Under PDE-5 Hormone Inhibitor Pills
  • Safety Measures To Ensure When Using PDE-5 Hormone Inhibitors
  • Possibilities Of Side Effects When Using PDE-5 Hormone Inhibitors
  • Which Medicine Among The PDE-5 Hormone Inhibitor Pills Category Is The Best?
  • Where To Buy PDE-5 Hormone Inhibitors?
  • Final say

PDE-5 inhibitors, do you know what drug group they belong to or what are the uses of such types of medicines? well, in this article we are going to give a detailed overview of the PDE-5 hormone inhibitor drugs and what their uses are.

We will also get to know about the precautions, doses, and possibilities of side effects if any when using such types of medicines. So let’s begin…

What Exactly Are PDE-5 Hormone-Inhibitory Drugs?

PDE-5 hormone inhibitor pills are a specific group of medicines that help in providing a strong and hard erection.

This group of medicines helps in curing the symptoms of erectile dysfunction which is a form of sexual disorder occurring in males. With this disorder, the ability to achieve a strong and hard erection is gone. Males suffering from such a sexual issue can have a deprived sexual life.

But you can now use PDE-5 hormone inhibitor pills such as Avanafil to recover from your problems and achieve strong erections sustained for longer periods. Such a medicine would cause a hard erection in impotent males and that is the purpose behind the use of such medicines.

Remember that all PDE-5 hormone inhibitor pills are prescription medicines. Hence if you are having the symptoms of ED already, don’t indulge in using an abrupt brand or dose of such medicines without consulting the doctors.

With a doctor's guidance, you will be recommended to use the right brand and dose suitable for your age and current health conditions.

Purpose Of Using PDE-5 Hormone Inhibitor Pills

As we mentioned above, the purpose of using PDE-5 hormone inhibitors is for ED issues in men.

The action of the PDE-5 hormone inhibitor pills enables a man suffering from ED to be able to temporarily shun any symptoms of erectile issues and get penile hardness.

No doubt that you must use such a medicine only before having sex and embracing your sexual lust and desires.

Some PDE-5 hormone inhibitor substances such as Tadalafil can have other reasons for usage as well.

Apart from curing erection issues such types of medicines can be also used for curing pulmonary arterial hypertension disorder, and benign prostatic hyperplasia issuesEven for such issues, the doctors need to be consulted first.

How Do PDE-5 Hormone Inhibitors Work?

Now, let us find out how the PDE-5 hormone inhibitor medicines would work. See, whenever you use any such medicine such as vardenfil it will cause the PDE-5 hormones to shut off. As the name suggests such medicines begin their action by cutting off the actions of the PDE-5 hormones.

Eventually, it is replaced by the cGMp hormone.

The cGMP hormone also activates nitric oxide that enables the blood vessels to be dilated causing a rise in blood flow. Within the penis tissues, this surge in blood flow causes higher sensitivity in the region and helps you to gain a hard erection when stimulated from the outside.

Popular Medicines And Categories Of Medicines Under PDE-5 Hormone Inhibitor Pills

Now that you know about the basic action of the PDE-5 hormone inhibitor pills and their uses it is time for us to check about the categories of PDE-5 hormone inhibitor pills in further detail.

See the group of PDE-5 hormone inhibitor drugs containing some substances such as Sildenafil, Tadalafil, vardenfil, and Avanafil.

These substances are not brand names but rather the composition of several other brands.


SildenafilVardenafilTadalafilAvanafil
Brand NameViagraLevitraCialisStendra
Major MetabolismCYP3A4CYP3A4
CYP3A4
CYP3A4
Why it’s recommended
Developed by Pfizer and most commonly used
Usually recommended for diabetics
Longest duration in comparison to all the ED drugs
Recommended if you need a fast treatment
Time to take effect
30-60 minutes
30-60 minutes
15-60 minutes
15 minutes
Duration of effect
4-6 hours
4-6 hours
Up to 36 hours
4-6 hours


Brands of ED medicines come in two categories. One is the generic category of medicines that contains all the branded names that have not yet been approved by the FDA.

Some of the common brand names under this category include:

  • Kamagra
  • Silditop
  • Suhagra
  • Cenforce
  • Fildena
  • Tadalista
  • Vidalista
  • Tastylia

And there is another category of ED medicines that has been recommended by the FDA for use.

Such brand names include the likes of:

Safety Measures To Ensure When Using PDE-5 Hormone Inhibitors

Whenever you are using any PDE-5 hormone inhibitor medicines it needs you to follow a certain basic set of guidelines.

You will need to avoid using the medicines above a stipulated dose as recommended by the doctors. Without taking your dose you don’t even stand a chance of achieving penile hardness either.

You are recommended not to make use of any addictive and habit-forming substances with PDE-5 hormone inhibitor drugs as they cause contraindications.

It is also not safe for your health to use such a class of medicines when you are already suffering from high blood pressure, cardiac problems, and severe liver and kidney disorders.

Possibilities Of Side Effects When Using PDE-5 Hormone Inhibitors

Yes, there are possibilities of having side effects whenever using PDE-5 hormone inhibitor pills.

you may get some of the mild side effects & major side effects of these medicines such as:

Mild Side Effects
Major Side Effects
headache
chest pain
dizziness
high blood pressure
nausea
cardiac pain
vomiting
vision blurring
diarrhea
lower libido
stomach cramps
priapism
dry mouth

palpitations

flushing

With such intense side effects the doctors may have to stop your course on the pills abruptly. Make sure to consult with the doctors regardless of the type and severity of the side effects.

The PDE-5 hormone inhibitor pills are not safe to use with certain other medicines such as blood thinners, or blood pressure-raising pills.

it is also not safe to use such medicines with those drugs that contain certain substances in them such as nitrate compounds or alpha and beta blockers. 

Which Medicine Among The PDE-5 Hormone Inhibitor Pills Category Is The Best?

Now, as you can see, when it comes to the PDE-5 hormone inhibitor pills, there is not just one but different brands of medicines with each one having its own dose. So which one of these should you prefer? well, this is where the instructions from the doctors can come in handy.

A doctor can help you to suitably recommend a safe dose depending on your health and age, and if any other pre-existing disorders are present.

Remember that the same brand or dose may not suit all. based on the severity of ED issues the dose would differ too. Most certainly you will have to use higher doses of any PDE-5 hormone inhibitor substances if your ED issues are severe.

Where To Buy PDE-5 Hormone Inhibitors?

To buy PDE-5 hormone inhibitor medicines you can avail of two options one is to buy the medicines online or buy it from your local pharmacy.

It entirely depends on your choice. But if you are to take our recommendation we would suggest you buy these medicines online because Medyplexpharma is a reputed online pharmacy are provides ED-curing medicines at cheaper prices. Check out the offers on multiple portals and find the best offers for you.

Final say

So, as you can see, in this article we have provided a deep insight into the PDE-5 hormone inhibitor pills and their possible uses. Remember to follow the set of guidelines that we have recommended in this article. Plus, depending on your health the doctors may advise you to follow a set of other precaution guidelines too.